This videohistory documents the Moore-Stein Protein Sequencer. The sequencer enabled automatic analysis of protein structure and was the forerunner of the automated instruments essential to modern biotechnology.
Arrangement:
Divided into 3 series: (1) Original videos; (2) Master videos; (3) Reference videos.
Biographical / Historical:
The first complete chemical analysis of a protein's primary structure was done on a small protein, insulin, by Frederic Sanger at Cambridge University for which he received the first of his two Nobel Prizes in 1958. The second protein structure to be completely analyzed was ribonuclease, done in the U.S. by Stanford Moore and William Stein at Rockefeller University, 1960.
Related Archival Materials:
The protein sequencer apparatus is located in the Division of Science Medicine, and Society (now Division of Medicine and Science).
Provenance:
Created by the Jerome and Dorothy Lemelson Center for the Study of Invention and Innovation, National Museum of American History, 1996.
Restrictions:
Collection is open for research but the original videos are stored off-site and special arrangements must be made to work with it. Contact the Archives Center for information at archivescenter@si.edu or 202-633-3270.
Rights:
Collection items available for reproduction, but the Archives Center makes no guarantees concerning copyright restrictions. Other intellectual property rights may apply. Archives Center cost-recovery and use fees may apply when requesting reproductions.
