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Curt I. Civin Video Documentation

Creator:
Vogelstein, Bert  Search this
Kinsler, Kenneth  Search this
Sharrer, Terry  Search this
Civin, Curt I.  Search this
Jerome and Dorothy Lemelson Center for the Study of Invention and Innovation.  Search this
Names:
Baxter Healthcare Corporation.  Search this
Becton Dickinson.  Search this
Johns Hopkins University  Search this
Extent:
0.25 Cubic feet
Type:
Archival materials
Collection descriptions
Videotapes
Oral history
Interviews
Date:
1997 June 5
Scope and Contents note:
Original videos documenting Curt I. Civins's discovery of the cell surface protein that makes stem cell selection possible; and interviews with Kenneth Kinsler and Bert Vogelstein.
Arrangement:
1 series.
Biographical/Historical note:
In the 1970s when Civin began stem cell research, little was known about progeniters, the cells of all other blood lineages. Civin thought that stem cells had their own identifying surface proteins. To test this, he immunized mice with leukemia cells, some of which he supposed might have that peculiar protein and then harvested the resulting immunoglobulins and reproduced them as monoclonal antibodies. In 1981, Civin discovered an antibody that bound to 1% of marrow cells.
Related Archival Materials:
Prototype of stem cell selector instrument housed in Division of Science and Medicine and Society.
Provenance:
National Museum of American History, Smithsonian Institution, Dept. of History.,Lemelson Center for the Study of Invention and Innovation, Room 1016, MRC 604, 12th & Constitution Ave., N.W., Washington, D.C. 20560.,Made for NMAH.,1997.3168.
Restrictions:
Collection is open for research.
Rights:
Collection items available for reproduction, but the Archives Center makes no guarantees concerning copyright restrictions. Other intellectual property rights may apply. Archives Center cost-recovery and use fees may apply when requesting reproductions. Signed releases in file.
Topic:
Tumors in children -- 1970-2000  Search this
Physicians -- 1950-2000  Search this
Stem cells  Search this
Oncology -- 1970-2000  Search this
Leukemia in children -- 1970-2000  Search this
Medicine -- 1970-2000  Search this
Cancer research -- 1970-2000  Search this
Cell growth -- 1970-2000  Search this
Genre/Form:
Videotapes -- 1990-2000
Oral history -- 1990-2000
Interviews -- 1980-2000
Citation:
Curt I. Civin Video Documentation, June 5, 1997, Archives Center, National Museum of American History.
Identifier:
NMAH.AC.0623
Archival Repository:
Archives Center, National Museum of American History
EDAN-URL:
ead_collection:sova-nmah-ac-0623

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  • Cancer research
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  • Baxter Healthcare Corporation.
  • Becton Dickinson.
  • Civin, Curt I.
  • Jerome and Dorothy Lemelson Center for the Study of Invention and Innovation.
  • Johns Hopkins University
  • Kinsler, Kenneth
  • Sharrer, Terry
  • Vogelstein, Bert
  • Baxter Healthcare Corporation.
  • Becton Dickinson.
  • Civin, Curt I.
  • Jerome and Dorothy Lemelson Center for the Study of Invention and Innovation.
  • Johns Hopkins University
  • Kinsler, Kenneth
  • Sharrer, Terry
  • Vogelstein, Bert
  • 1990s
  • Archives Center, National Museum of American History