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Curt I. Civin Video Documentation, June 5, 1997

Creator:
Jerome and Dorothy Lemelson Center for the Study of Invention and Innovation
Interviewer:
Sharrer, Terry
Interviewee:
Kinsler, Kenneth
Vogelstein, Bert
Civin, Curt I
Subject:
Baxter Healthcare Corporation
Johns Hopkins University
Becton Dickinson
Physical description:
0.25 cu. ft.: 1 box
Type:
Videotapes
Collection descriptions
Interviews
Oral histories (document genres)
Date:
1997
June 5, 1997
1970-2000
1950-2000
1990-2000
1980-2000
Notes:
In the 1970s when Civin began stem cell research, little was known about progeniters, the cells of all other blood lineages. Civin thought that stem cells had their own identifying surface proteins. To test this, he immunized mice with leukemia cells, some of which he supposed might have that peculiar protein and then harvested the resulting immunoglobulins and reproduced them as monoclonal antibodies. In 1981, Civin discovered an antibody that bound to 1% of marrow cells.
Summary:
Original videos documenting Curt I. Civins's discovery of the cell surface protein that makes stem cell selection possible; and interviews with Kenneth Kinsler and Bert Vogelstein.
Cite as:
Curt I. Civin Video Documentation, June 5, 1997, Archives Center, National Museum of American History
Topic:
Stem cells
Oncology
Medicine
Cell growth
Tumors in children
Cancer research
Leukemia in children
Physicians
Local number:
1997.3168 (NMAH Acc.)
Data Source:
Archives Center - NMAH

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