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History of the Polymerase Chain Reaction Videohistory Collection 1992-1993

Online Media

Catalog Data

Creator:
Mullis, Kary B  Search this
Gefland, David H  Search this
Faloona, Fred  Search this
DiCesare, Joseph L  Search this
Haff, Lawrence Allen  Search this
Pigliucci, Riccardo  Search this
Barrett, Peter  Search this
Atwood, John G  Search this
Kwok, Shirley  Search this
White, Thomas J  Search this
Saiki, Randall K  Search this
Arnheim, Norman  Search this
Erlich, Henry Anthony  Search this
Jones, David C  Search this
Katz, Elena D  Search this
Seyfried, Donna Marie  Search this
Sninsky, John J  Search this
Scharf, Stephen  Search this
Watson, Robert  Search this
Woudenberg, Timothy M  Search this
Widunas, Joseph  Search this
Regusa, Robert P  Search this
Grossman, Robert L  Search this
Kelley, Lesley S  Search this
Leath, Richard  Search this
Pasahow, Lynn H  Search this
Picozza, Enrico  Search this
Interviewer:
Kondratas, Ramunas  Search this
Subject:
Mullis, Kary B  Search this
Gefland, David H  Search this
Faloona, Fred  Search this
DiCesare, Joseph L  Search this
Haff, Lawrence Allen  Search this
Pigliucci, Riccardo  Search this
Barrett, Peter  Search this
Atwood, John G  Search this
Kwok, Shirley  Search this
White, Thomas J  Search this
Saiki, Randall K  Search this
Arnheim, Norman  Search this
Erlich, Henry Anthony  Search this
Jones, David C  Search this
Katz, Elena D  Search this
Seyfried, Donna Marie  Search this
Sninsky, John J  Search this
Scharf, Stephen  Search this
Watson, Robert  Search this
Woudenberg, Timothy M  Search this
Widunas, Joseph  Search this
Regusa, Robert P  Search this
Grossman, Robert L  Search this
Kelley, Lesley S  Search this
Leath, Richard  Search this
Pasahow, Lynn H  Search this
Picozza, Enrico  Search this
Cetus Corporation  Search this
Perkin-Elmer Corporation  Search this
Roche Molecular Systems  Search this
Hoffman-La Roche Corporation  Search this
DNA Thermal Cycler  Search this
History of the Polymerase Chain Reaction  Search this
Physical description:
11 videotapes
Type:
Interviews
Collection descriptions
Videotapes
Oral history
Date:
1992
1992-1993
Notes:
The Polymerase Chain Reaction (PCR) technique was invented in 1985 by Kary B. Mullis, a chemist at the Cetus Corporation, a biotechnology firm in Emeryville, California. PCR allowed scientists to make millions of copies of a scarce sample of DNA. Although revolutionary, Mullis' technique proved to be slow and labor-intensive, and Cetus scientists soon automated the process with the creation of the first thermocycling machine, MR. CYCLE. In 1985, Cetus formed a joint venture with the Perkin-Elmer Corporation in Norwalk, Connecticut, and introduced the DNA Thermal Cycler. On January 15, 1989, Cetus announced an agreement to collaborate with Hoffman-La Roche on the development and commercialization of in vitro human diagnostic products and services based on PCR technology. The PCR patent and associated technology was later purchased by Roche Molecular Systems.
(1) Description in control file; (2) name index to transcript.
Organization:
(1) VHS tapes, 19 hours; (2) transcript, 346 pages
Summary:
Ramunas A. Kondratas, National Museum of American History, documented the discovery, development, commercialization, and applications of PCR technology. Interviewees included Kary B. Mullis, Norman Arnheim, John G. Atwood, Peter Barrett, Joseph L. DiCesare, Henry Anthony Erlich, Fred Faloona, David H. Gefland, Lawrence Allen Haff, David C. Jones, Elena D. Katz, Shirley Kwok, Richard Leath, Lynn H. Pasahow, Enrico Picozza, Riccardo Pigliucci, Randall K. Saiki, Donna Marie Seyfried, John J. Sninsky, Stephen Scharf, Robert Watson, Thomas J. White, Timothy M. Woudenberg, Joseph Widunas, Robert P. Regusa, Robert L. Grossman, and Lesley S. Kelley.
Topics discussed include the invention of the PCR technique, early applications, PCR patent rights, Perkin-Elmer's joint venture with Cetus, the design and engineering of commercial thermocyclers, marketing, and future applications.
Repository Loc.:
Smithsonian Institution Archives, Capital Gallery, Suite 3000, MRC 507; 600 Maryland Avenue, SW; Washington, DC 20024-2520
Topic:
History of science and technology  Search this
Molecular biology  Search this
Biotechnology  Search this
Bioengineering  Search this
Scientific apparatus and instruments  Search this
Patents  Search this
Local number:
SIA RU009577
Data Source:
Smithsonian Institution Archives
EDAN-URL:
edanmdm:siris_arc_217745